More people are using marijuana as a substitute for traditional pharmaceuticals—and so are man’s best friend: dogs.
To date, there’s been limited research into the effects of administering cannabis to pets. But a recent study, published in the journal Frontiers last month, offers new details about how cannabidiol (CBD) oil can alleviate the symptoms of osteoarthritis in dogs.
Researchers at Cornell University recruited 22 dogs with osteoarthritis—a condition characterized by inflammation caused by the deterioration of muscle tissue connected to bone joints—and administered different doses of hemp-derived CBD oil as part of a “randomized, placebo-controlled, owner and veterinarian double-blind, cross-over trial.”
The results appear to confirm what many pet owners who’ve given their dogs CBD have anecdotally reported: It helps. Throughout the experiment, researchers relied on licensed veterinarians, as well as the pet owners, to document each dog’s pain status and activity.
The study “showed that CBD oil increase comfort and activity in the home environment for dogs with [osteoarthritis],” the study authors wrote. “Additionally, veterinary assessments of pain were also favorable.”
While news reports have circulated about the dangers of accidental pet ingestion of psychoactive THC-infused marijuana products, the researchers didn’t observe any serious, adverse side effects from the CBD-focused treatment. Some dogs received 2 milligrams of CBD per kilogram twice daily, others received 8 milligrams of CBD per kilogram twice daily, and a control group received a placebo oil. The dogs who got the CBD seemed to do just fine.
The only side note is that researchers observed “incidental rises in alkaline phosphatase that could be related to the treatment” for some of the dogs when they tested their blood.
Still, CBD may prove to be a preferable treatment options for some dogs with osteoarthritis. The condition is typically treated with non-steroidal anti-inflammatory (NSAID) painkillers, which can cause problems with the kidney and gut, the researchers noted.
Why this study matters.
There’s growing interest among pet owners in the potential benefits of CBD treatment for a variety of conditions—from arthritis to anxiety to epilepsy.
Several cannabis companies specifically market their CBD products toward pets. (This study was funded via a grant to Cornell University by Ellevet LLC, a company that produces cannabis pet treats). But because marijuana remains illegal under federal law, veterinarians risk losing their licenses if they recommend marijuana-based products.
At the same time that more research is coming out about the potential medical applications of cannabis in humans, other recent studies have bolstered anecdotal accounts about the benefits of cannabis for pets. For example, a preliminary report from Colorado State University found that CBD can reduce the frequency of seizures in epileptic dogs by as much as 89 percent.
And earlier this month, a Canadian company received government approval to test CBD-infused pet food as a means of mitigating anxiety among dogs, Newsweek reported.
To be sure, not all ingredients in marijuana affect animals in the same way that they affect humans. But this and other recent research is giving pet owners eager for alternative treatment options some relief, showing that cannabis can, in fact, provide some relief for dogs without serious side effects.
See the original article published on Marijuana Moment below:
Dogs With Arthritis Benefit From Cannabis Oil, Study Says
Photo by Matt Nelson on Unsplash
A lot of time and money goes into marijuana research. But what if I told you that you could take a nug of weed, place it in an espresso machine and extract cannabis ingredients in under one minute?
OK, that’s an oversimplified description. Still, it’s more or less what a team of researchers was able to accomplish in a recent experiment detailed in a manuscript due to be published in The International Journal of Pure and Applied Analytical Chemistry.
Via The International Journal of Pure and Applied Analytical Chemistry.
The team wanted to test whether espresso-based extraction—a novel and relatively inexpensive analytic method, raved about in scientific literature—could be applied to marijuana. And it turns out that it can!
You don’t need a fancy, $2,000 setup, either. For the experiment, the researchers used a Nespresso Essenza Manual XN2003 machine, which goes for about $300 on eBay. (It’s not currently available on Amazon, though—possibly because they’ve all been snatched up by the chemist community).
“The use of hard cap espresso machines has been recently proposed for analytical extractions due to its easy use, speed, availability and low price, providing efficient extraction of organic compounds from solid samples in few seconds,” the researchers wrote.
Seized cannabis provided by Unidad de Inspección de Farmacia y Control de Drogas del Área de Sanidad in Valencia, Spain, was inserted into the filter after a thorough cleaning. The hard cap espresso machine was used to extract three main ingredients from the plant (THC, CBD and CBN).
Then the results of those extracts were cross-referenced with extractions of the same sample using three different, more traditional methods: Ultrasound-assisted extraction, gaschromatography-mass spectrometry and ion mobility spectrometry (IMS).
And consistent with results from non-marijuana-related studies, the extraction method seemed to work—in under one minute.
“It has been evidenced that the developed method for the major cannabinoids extraction is a really encouraging example of the wide range of possibilities that a conventional and low cost hard cap espresso assisted extraction could offer in analytical laboratories,” according to the study.
“The quantitative extraction of THC, CBD and CBN from buds, leaves and stems has been achieved in a single and fast extraction of 40 seconds.”
The researchers noted that after using a rigorous multi-step cleaning method, the coffee machine has been “used in our laboratory during the last two and a half years without observing any damage or incident.”
See the original article published on Marijuana Moment below:
Scientists Discover You Can Use Espresso Machines To Make Marijuana Extracts
As cannabidiol (CBD) oil continues to become a more prominent treatment option for newly born babies with severe illnesses, like epilepsy, the news cycle also reveals more and more devastating tales about barely born children fighting for their lives.
Although there are many happy examples of cases in which targeted cannabinoid therapies, like CBD oil, significantly improved the life of a child, unfortunately it is not a cure-all and sometimes these stories do not have happy endings.
Eight-month-old Mary Jane Pierce passed away from natural causes on Friday February 19 while being treated with CBD oil at the B.C. Children’s Hospital in Vancouver.
This article was written in loving memory of Mary Jane Pierce.
Born prematurely at just 25 weeks, Mary Jane Pierce suffered from “serious health problems, including brain bleeding, cerebral palsy, and severe seizures.” At such a young age, Mary Jane was at the center of controversy regarding the use of CBD oil in Canadian hospitals. Her parents, Michelle and Justin, experienced benefits in the treatment of their own epilepsy using cannabis oil, so they fought to be able to give it to Mary Jane.
Being so young and so ill doctors did not believe Mary Jane would survive and they wanted to remove her from life support. As a result, Michelle and Justin were forced to file a temporary injunction to keep Mary Jane on life support. They won the injunction, but were relieved to drop it in September because her health was improving with the use of CBD oil. Although there was improvement, ultimately, Mary Jane was not able to overcome her health obstacles.
Sadly, Mary Jane isn’t the only infant fighting for his or her life with cannabis oil therapy. Just recently, a two-month-old in Colorado with a very severe, rare form of epilepsy became one of the youngest marijuana patients in the United States.
While cannabinoid therapies have the potential to heal or improve the conditions of some children (and adult)s, just as with any medicine, sometimes the obstacles are too much to overcome.
Image via CBC.CA
As far as cannabis is concerned, I am a snobby, outspoken, flower enthusiast. If you grant me the option of cannabis flower or one of its many derivatives, I’ll yell “take me to the source!” My old-school sentiments do not, however, preclude me from occasionally trying one of the many cannabis derivatives that grace today’s modern cannabis society, which brings me to the O.penVAPE RESERVE Cartridge.
At first glance, the O.penVAPE RESERVE looks like any other O.penVAPE vaporizer. The new device is the same sleek, discreet, black vape pen that O.penVAPE helped to develop as the standard for basic cannabis vaporizers.
So what makes the O.penVAPE RESERVE Cartridge stand out from the crowd? Until very recently, most of O.penVAPE’s vaporizer pens used cannabis concentrate cartridges that included polyethylene glycol, a common vape product additive which helps to maintain a physical state conducive to vaporizing. In recent years, however, there has been controversy regarding the safety of additive inhalation; and so began the race to find an alternative. The O.penVAPE RESERVE line did away with polyethylene glycol entirely to create a pure cannabis oil cartridge for the choosy cannoisseur.
Unlike many vaporizers currently on the market, the O.penVAPE RESERVE uses cannabis concentrate cartridges that purely consist of cannabis oil. As I mentioned above, the vaporizer maintains the same look, feel, and usability that consumers have come to expect from O.penVAPE products. The pen is still easy to assemble with only two components – the cartridge and battery – which screw into each other. A third, USB component can be screwed into the battery when the device must be recharged.
Once charged, the O.penVAPE RESERVE is incredibly easy to use as there are no buttons to push, and a light at the bottom of the pen signals when the pen is in use, overheats, or needs to be recharged. The O.penVAPE RESERVE has maintained its discreet form (my favorite feature), which allows both patients and recreational users to consume at times and places they may not otherwise be able.
The most noticeable difference in appearance is how much thicker and darker the concentrate in the RESERVE cartridge is without any additives. For me, this is reassuring in that it is looks as I’ve come to expect cannabis concentrates to appear.
Drawing on the O.penVAPE RESERVE requires just a little more strength than the original, given the thicker concentrate, but the RESERVE product rewards you for your extra effort by smoking more like a load-your-own vaporizer or even an actual dab. The pure concentrate has a clean oil flavor that lets the terpenes shine through. The O.penVAPE RESERVE also offers a more robust smoke that the consumer will definitely feel accompanied by an oddly satisfying increase in the amount of smoke exhaled. If you are a seasoned smoker, you probably prefer to feel each drag and subsequent exhale without feeling like you’re inhaling unnecessary chemicals. On these marks, O.penVAPE RESERVE delivers.
For this review, I sampled the Aspen OG 420 mg (420, nice) RESERVE cartridge, which is a sativa concentrate on the sweeter, robust side; O.penVAPE RESERVE also offers other sativa, hybrid, and indica concentrate cartridges that are strain specific, so there is something for all different types of consumers. In this case, the Aspen OG gave me a moderately uplifting high that effectively amounted to an afternoon pick-me-up and was accompanied by physical sensations in my head and chest. I never felt like I was zoned out or ultra focused, but I was definitely high and energized from just a couple tokes.
Overall, I would say the Aspen OG cartridge stoned me without rendering me dysfunctional, which is perhaps the perfect combination for a product that is often used in situations where discretion is necessary. More importantly, I felt good about using the O.penVAPE RESERVE because I knew I was consuming pure cannabis oil. I would highly recommend the O.penVAPE RESERVE products to individuals who currently vaporize but are looking for something cleaner and with a more pronounced smoking experience. I would also encourage those who need to be discreet in their cannabis consumption to check out the O.penVAPE RESERVE as, in my opinion, it is the perfect compliment to the clandestine cannoisseur’s paraphernalia collection.
Amylea Nunez, a two-month old baby girl suffering from a rare form of epilepsy, is now the world’s youngest medical cannabis patient. Amylea had her first seizure just a day after she was born, and she has been surviving in neonatal intensive care units ever since.
Unable to receive proper medical treatment in their hometown of Albuquerque, New Mexico, Amylea’s parents transferred her to the Children’s Hospital in Aurora, Colorado in hopes of trying an alternative form of medicine. The alternative treatment is CBD (cannabidiol) cannabis oil. CBD is the non-psychoactive cannabinoid in marijuana that is now more commonly used to treat severe childhood epilepsy because of its proven success in reducing the frequency and severity of seizures. CBD is non-psychoactive, unlike THC, meaning it does not produce the euphoric effect commonly described as the high, so parents, doctors and even politicians are more comfortable with giving it to children.
After Amylea’s parents pushed hard for it, the hospital finally green-lit the CBD oil treatment case study, and the Nunez family was able to begin administering cannabis oil. The cannabis oil being given to Amylea is made from Charlotte’s Web, the CBD-rich cannabis strain that made national headlines when Dr. Sanjay Gupta explored its medical efficacy for CNN. Thus far, nurses have reported that Amylea seems “more alert than usual” after just two doses.
Amylea’s parents report that the cannabis oil experiment has been miraculous.
“For us to get the approval for us to administer it while she is in the NICU while she’s a patient…it’s kind of like a miracle,”
Nicole Nunez, Amylea’s mother said.
“Because they were completely against it saying, ‘No you can’t do it, you have to wait until she’s an out-patient.”
The Nunez family plans to continue using the medicinal cannabis oil treatment for at least the next four months. Amylea’s rare form of epilepsy remains undiagnosed at this time and her case is by far the youngest public one of its kind. This may become a defining case in history which influences parents waffling over similar decisions in the future.
Clearly a gut-wrenching tale, if Amylea’s condition improves with the use of cannabis oil when more modern medicines failed, doctors may feel more comfortable prescribing cannabinoid medicines, like oil concentrates, to babies in the future.
Donations are being accepted to help cover the high costs of Amylea’s medical treatments. Amylea’s family has only raised about half of their $20,000 goal thus far. Click this link to donate through her GoFundMe page. Even small amounts like $5, $10 and $2o will add up, so any small amount will help.
Cannabis is actually one of the oldest known medicines in the world with documented use dating back 10,000 years, and cannabis tinctures were readily available over-the-counter in the United States until the 1930s. Click here to meet the man responsible for cannabis prohibition in the United States and several other countries throughout the world.
Image via KRQE