A new study has some good news for people who fear public speaking—or suffer from acute anxiety in general. The marijuana component cannabidiol, or CBD, seems to help.
The study, published in the Brazilian Journal of Psychiatry, tested how CBD influences anxiety in a simulated public speaking setting, “a well-tested anxiety-inducing method.”
The researchers analyzed self-reported anxiety test results as well as physiological markers like blood pressure and heart rate in 57 male subjects throughout the experiment. Participants received either 150mg, 300mg or 600mg of CBD, or a placebo in the randomized, double-blind test.
Earlier research has demonstrated that CBD can mitigate anxiety in a dose-dependent manner. The present study reached the same conclusion: The impact of CBD on anxiety followed a U-shaped dose-response curve.
Here’s how the experiment worked.
Participants were shown an instructional video and given two minutes to come up with a four-minute speech about public transportation in their neighborhood. Anxiety markers were tested before, in the middle of and after their speeches.
Self-reports about anxiety levels showed that the group that received the 300mg CBD dose “showed lower anxiety levels” compared to the placebo group. Also, the higher (600mg) and lower (150mg) dose “had little or no effect on [public speaking] anxiety, and a significant response was only achieved with an intermediate dose.”
Via the Brazilian Journal of Psychiatry.
“Confirming several preclinical and clinical studies, our results indicate that acute doses of CBD can decrease anxiety,” the researchers wrote.
“In conclusion, we observed again that single acute doses of CBD cause an inverted U-shaped dose-response pattern in human subjects submitted to an experimental model of anxiety,” the study found. “The narrow therapeutic window of CBD makes it difficult to use the drug in clinical settings before rigorous chronic dose-response clinical trials have established optimal doses.”
See the original article published on Marijuana Moment below:
Marijuana Ingredient Reduces Anxiety During Public Speaking, Study Shows
More people are using marijuana as a substitute for traditional pharmaceuticals—and so are man’s best friend: dogs.
To date, there’s been limited research into the effects of administering cannabis to pets. But a recent study, published in the journal Frontiers last month, offers new details about how cannabidiol (CBD) oil can alleviate the symptoms of osteoarthritis in dogs.
Researchers at Cornell University recruited 22 dogs with osteoarthritis—a condition characterized by inflammation caused by the deterioration of muscle tissue connected to bone joints—and administered different doses of hemp-derived CBD oil as part of a “randomized, placebo-controlled, owner and veterinarian double-blind, cross-over trial.”
The results appear to confirm what many pet owners who’ve given their dogs CBD have anecdotally reported: It helps. Throughout the experiment, researchers relied on licensed veterinarians, as well as the pet owners, to document each dog’s pain status and activity.
The study “showed that CBD oil increase comfort and activity in the home environment for dogs with [osteoarthritis],” the study authors wrote. “Additionally, veterinary assessments of pain were also favorable.”
While news reports have circulated about the dangers of accidental pet ingestion of psychoactive THC-infused marijuana products, the researchers didn’t observe any serious, adverse side effects from the CBD-focused treatment. Some dogs received 2 milligrams of CBD per kilogram twice daily, others received 8 milligrams of CBD per kilogram twice daily, and a control group received a placebo oil. The dogs who got the CBD seemed to do just fine.
The only side note is that researchers observed “incidental rises in alkaline phosphatase that could be related to the treatment” for some of the dogs when they tested their blood.
Still, CBD may prove to be a preferable treatment options for some dogs with osteoarthritis. The condition is typically treated with non-steroidal anti-inflammatory (NSAID) painkillers, which can cause problems with the kidney and gut, the researchers noted.
Why this study matters.
There’s growing interest among pet owners in the potential benefits of CBD treatment for a variety of conditions—from arthritis to anxiety to epilepsy.
Several cannabis companies specifically market their CBD products toward pets. (This study was funded via a grant to Cornell University by Ellevet LLC, a company that produces cannabis pet treats). But because marijuana remains illegal under federal law, veterinarians risk losing their licenses if they recommend marijuana-based products.
At the same time that more research is coming out about the potential medical applications of cannabis in humans, other recent studies have bolstered anecdotal accounts about the benefits of cannabis for pets. For example, a preliminary report from Colorado State University found that CBD can reduce the frequency of seizures in epileptic dogs by as much as 89 percent.
And earlier this month, a Canadian company received government approval to test CBD-infused pet food as a means of mitigating anxiety among dogs, Newsweek reported.
To be sure, not all ingredients in marijuana affect animals in the same way that they affect humans. But this and other recent research is giving pet owners eager for alternative treatment options some relief, showing that cannabis can, in fact, provide some relief for dogs without serious side effects.
See the original article published on Marijuana Moment below:
Dogs With Arthritis Benefit From Cannabis Oil, Study Says
Photo by Matt Nelson on Unsplash
Despite being legally permitted to have and use medical marijuana in oil form, patients in Georgia have hit a roadblock when it comes to state law. While enrollees in the state’s growing medical marijuana program can legally possess low THC cannabis oil, they are not permitted to purchase or grow it; they are also not permitted to order it from another state and have it delivered.
An Unlikely Hero Emerges
Faced with the prospect of letting people who were already ill suffer, Republican Representative Allen Peake stepped up to make a difference. This Macon, GA lawmaker is taking advantage of some grey areas in the state’s marijuana laws to help sick constituents who have no other way to access the medical cannabis they need to relieve their symptoms. Hundreds of local residents rely on state representative Allen Peake for medical marijuana products each month. Rep. Peake hopes to be able to continue to provide this much-needed medication for the ill people he serves.
The recipients of the cannabis oil imported from Colorado by this compassionate lawmaker are legally allowed to have the substance under the state law, but simply have no legal way to acquire it. Peake spoke with the Associated Press recently and revealed why he got into to the underground medical marijuana business – and why he continues to act in defiance of the law.
Under Rep. Peake’s stewardship, Georgia’s medical marijuana program has grown; it now provides cannabis oil with a low level of THC to over a thousand ill patients in the region. There is one problem, though – patients enrolled in the program are permitted to have and use medical marijuana, they just can’t grow it, buy it or have it sent in from another state.
Meet Unlikely Cannabis Dealer, Allen Peake
Rep. Allen Peak holds up a bottle of cannabis oil. (The Telegraph photo)
Restaurant CEO and state representative Allen Peake is an unlikely candidate for rule breaking; he runs his business and his life based on Christian and biblical principles. He discovered the plight of the residents he now serves by accident; families were coming to him for help moving all the way to Colorado simply to legally access the medical marijuana they need.
Now, each month, boxes full of cannabis oil arrive at Peake’s office for distribution to the ailing residents he serves. According to Peake, he is not sure where the medication comes from; he is just grateful to be able to distribute it to those in need.
Skirting the Law for the Greater Good
While marijuana is legal for medical use in Georgia, transporting this Schedule 1 narcotic across state lines remains a felony.
While Peake doesn’t know where those boxes come from, he makes a big donation to a Colorado based medical cannabis research foundation every time they arrive. By making a donation, he is able to ensure the oil continues to flow – without making official payments (which would be illegal in Georgia).
By donating money for the oil and then giving it away for free, Peake avoids being charged with selling marijuana. Under current laws, the gifting of cannabis oil for free is allowed. Peake continues to be at the forefront of the fight to legalize medical marijuana in Georgia and is working hard to expand the qualifying conditions a patient can have to legally enroll in a program.
Over 1200 patients are currently enrolled in the state’s medical marijuana program and many of them turn to Peake to access the products they need. As the precious oil is delivered, Peake is vigilant about checking to make sure the recipients are properly registered and enrolled in Georgia’s medical marijuana program and that
they can legally possess and use the product.
This Republican lawmaker continues to be an unlikely champion for the cause of medical marijuana. He has no plans on ending his crusade to help patients in Georgia – or on stopping the mystery deliveries that provide patients with the cannabis oil they need to function each day.
A little over a month ago, Wisconsin’s lawmakers voted on a bill that would allow patients with specific conditions to possess and use CBD oil with a physician’s recommendation. At the time there was only one vote against it out of both chambers – which was a big deal after prior legislation a couple years back had been significantly voted against. The bill was then sent over to Governor Scott Walker, who has just finally signed the bill into law this week, making it official that CBD oil is legal for patients to use in Wisconsin.
“Today, we’re making it easier for people in our state to obtain CBD oil without a psychoactive effect to treat a medical condition as advised by their doctor,”
Walker said in a statement.
Unfortunately, there are a few downsides to this particular law; the biggest one being a lack of in-state production and dispensing of the oil. The bill did not create any means for licensing cultivation facilities, processing companies or dispensaries – meaning it creates no legal access to the medicine patients so desperately need. It also doesn’t specify where patients are expected to obtain the oil – whereas some states with similar legislation in place have at least made a suggestion (such as nearby states), even when that suggestion is to break federal law and cross state lines with the cannabis oil.
Parents with children suffering from seizure conditions may be able to rest easy about what would happen if they were discovered to have CBD oil – but this bill really doesn’t make as much of a difference as lawmakers would like to think. Until there is a safe and legal way for patients to access the cannabis oil there will still be the question of how they are supposed to get the medicine once a physician finally gives them the go-ahead for treatment.
In states with CBD laws like this the only option is to get it illegally, either from someone in state on the illegal market or from a state that will accept out of state medical marijuana registration cards. This doesn’t save parents from having to be criminals just to medicate their children – it only provides protection once they are already in possession of the medicine and that’s just not enough.
While it is a great thing to see lawmakers nearly unanimously make the decision to go against allow patients suffering from seizure conditions to use CBD oil, it is honestly not doing enough to really help these patients.
Originally published: The Marijuana Times
In a shocking turn of events, both the Indiana House and Senate have approved a bill to legalize the possession and use of cannabidiol (CBD) oil for those suffering from treatment resistant epilepsy in the Hoosier State.
Multiple medical cannabis bills have been introduced to the Indiana Legislature the past few years, but none have even received a hearing. This time though, the House passed the bill unanimously 95 to zero. In the same day, the Senate voted 35 to 13 in support.
Families with children suffering from severe forms of epilepsy, living in Indiana, have reportedly been pushing for this CBD-only law to be approved so that their children may have access to this treatment option. CBD is the non-psychoactive cannabinoid in cannabis that has received national recognition for reducing the duration as well as the total number of seizures suffered by children with epilepsy. Because it is non-psychoactive, CBD oil does not produce the high associated with full potency marijuana that contains higher percentages of THC.
Written by 42 representatives and sponsored by five more, House Bill 1148, would allow those suffering from ‘treatment resistant epilepsy’ to possess and use CBD oil if a state-approved physician recommends it. The department of heath would be responsible for keeping track of those registered as CBD oil patients.
Not signed into law yet, a committee is tasked with deciding what percentage of THC will be allowable, and then it will head to the governor’s desk for consideration.